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NeuroDevNet researchers have made the first steps towards identifying an epigenetic signature for Fetal Alcohol Spectrum Disorder (FASD), drawing from the largest-ever study of children and youth exposed to alcohol before birth.

The multi-disciplinary group found a diverse pattern of DNA methylation that possibly indicates modified genetic expression in 110 children diagnosed with FASD, or known to have a history of prenatal alcohol exposure, compared to 96 age- and sex-matched controls aged 5-18. 

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NeuroDevNet welcomes Dr. Sheila Laredo as our new Chair of the Board of Directors.

Upon joining the board in 2013, Dr. Laredo brought a wealth of experience as a clinician with a primary interest in women’s reproductive health, and immersion in neurodevelopmental issues as a seasoned advocate and parent of two children on the autism spectrum.

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Findings emerging from ongoing work by Autism Research Group Co-Lead Dr. Stephen Scherer, colleague Dr. Ryan Yuen, and collaborators indicate that clusters of de novo, or new mutations in the genome of mothers likely to contribute to autism.

“Genome-wide characteristics of de novo mutations in autism,” published August 3 in npj |Genomic Medicine is the largest-yet whole genome study of autism, involving data from 200 children and their unaffected parents.

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